Dose response of ipratropium bromide assessed by two methods
نویسندگان
چکیده
منابع مشابه
Dose-response comparison of ipratropium bromide from a metered-dose inhaler and by jet nebulisation.
The dose-response relationships of the anticholinergic bronchodilator drug ipratropium bromide were studied. Cumulative doses totalling 288 micrograms ipratropium were given by inhalation of a liquid aerosol from a Wright nebuliser to each of 10 patients with stable, moderately severe airflow obstruction. Up to 80% of the maximum achievable bronchodilator response, as assessed by a rise in the ...
متن کاملAnisocoria with high dose ipratropium bromide inhaler.
I bromide is an atropine derived anti-cholinergic bronchodilator used in obstructive lung diseases. Anisocoria mainly caused by the direct effect of nebulized ipratropium bromide via a leaking mask has been well described in the literature.1,2 However, anisocoria induced by systemic absorption after long-term use of high dose ipratropium inhaler is not well reported. We report a case of a 24-ye...
متن کاملBronchoconstriction in response to ipratropium bromide.
Pyke DA, Leslie RDG. Chlorpropamide-alcohol flushing: a definition of its relation to non-insulin-dependent diabetes. Br Med J 1978;ii: 1521-2. 2 Barnett AH, Pyke DA. Chlorpropamide-alcohol flushing and large-vessel disease in non-insulin-dependent diabetes. Br MedJ7 1980;281:261-2. 3 Jerntorp P, Almer L-O. Chlorpropamide-alcohol flushing in relation to macroangiopathy and peripheral neuropathy...
متن کاملEffect of four weeks' high dose ipratropium bromide
In a randomised, double blind crossover study the effect of high dose ipratropium bromide (200 pg three times daily given by metered dose inhaler for four weeks) on lung mucociliary clearance and on the wet weight and mean apparent viscosity of sputum was compared with that of placebo. Six smokers, six ex-smokers, and three non-smokers (12 men and three women, median age 60 years) were studied....
متن کاملBladder outflow obstruction induced by ipratropium bromide.
Three cases are described in which bladder outflow obstruction was produced by ipratropium bromide, a widely used anticholinergic bronchodilator which has been regarded as virtually free from systemic side effects. Many patients treated with ipratropium bromide are elderly males in whom prostatic hypertrophy is common and in these circumstances, large doses should be used with caution.
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ژورنال
عنوان ژورنال: Thorax
سال: 1980
ISSN: 0040-6376
DOI: 10.1136/thx.35.2.137